What did we find?

Ignatenko O, Malinen S, Rybas S, Vihinen H, Nikkanen J, Kononov A, Jokitalo ES, Ince-Dunn G, Suomalainen A. Mitochondrial dysfunction compromises ciliary homeostasis in astrocytes.
J Cell Biol 2023

Nikkanen J, Leong YA, Krause WC, Dermadi D, Maschek JA, Van Ry T, Cox JE, Weiss EJ, Gokcumen O, Chawla A, Ingraham HA. An Evolutionary Trade-Off Between Host Immunity and Metabolism Drives Fatty Liver in Male Mice.
Science 2022.

Ganeshan K*, Nikkanen J*, Man K*, Leong YA*, Sogawa Y, Maschek JA, Van Ry T, Chagwedera DN, Cox JE, Chawla A. Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance.
Cell 2019. *co-first

Nikkanen J, Landoni JC, Balboa D, Haugas M, Partanen J, Paetau A, Isohanni P, Brilhante V, Suomalainen A. A complex genomic locus drives mtDNA replicase POLG expression to its disease-related nervous system regions.
EMBO Mol Med 2018.